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In case of strongly increased ROS concentrations, these types of damage can occur in close proximity to each other on both DNA strands, resulting in DNA DSB (Cannan et al., 2014

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Helps Support Immune Function The immune system depends on healthy cells to function efficiently

For instance, a posterior communicating artery aneurysm that is compressing the oculomotor nerve might cause double vision

Interestingly, upregulation of the protein TTYH3, a calcium-activated chloride channel, was also recently reported in homozygous Cln3 ex7/8/ex7/8 microglia [41], strengthening the hypothesis of a connection between CLN3 loss and TTYH3 induction